Chiamvimonvat, N., C.-M. Ho, H.-J. Tsai and B.D. Hammock. 2007. The soluble epoxide hydrolase as a pharmaceutical target for hypertension. J. Carviovasc. Pharm. 50:225-237.

Huang, H., C. Morisseau, J.F. Wang, T. Yang, J.R. Falck, B.D. Hammock and M.-H. Wang. 2007. Increasing or stabilizing renal epoxyeicosatrienoic acid production attenuates abnormal renal function and hypertension in obese rats. Am. J. Physiol.-Renal. 293:342-349. doi:10.1152/ajprenal.00004.2007

Zhang, W., I.P. Koerner, R. Noppens, M. Grafe, H.-J. Tsai, C. Morisseau, A. Luria, B.D. Hammock, J.R. Falck and N. Alkayed. 2007. Soluble epoxide hydrolase: A novel therapeutic target in stroke. J. Cerebr. Blood F. Met. April 18:1-10.

Loch, D., A. Hoey, C. Morisseau, B. Hammock and L. Brown. 2007. Prevention of hypertension in Doca-salt rats by an inhibition of soluble epoxide hydrolase. Cell. Biochem. Biophys. 47:87-97.

Schmelzer, K.R., B. Inceoglu, L. Kubala, I.-H. Kim, S.L. Jinks, J.P. Eiserich and B.D. Hammock. 2006. Enhancement of antinociception by coadministration of nonsteroidal anti-inflammatory drugs and soluble epoxide hydrolase inhibitors. Proc. Natl. Acad. Sci. USA. 103:13646-13651.

Dorrance, A.M., N. Rupp, D.M. Pollock, J.W. Newman, B.D. Hammock and J.D. Imig. 2005. An epoxide hydrolase inhibitor, 12-(3-Adamantan-1-yl-ureido) dodecanoic acid (AUDA) reduces ischemic cerebral infarct size in stroke-prone spontaneously hypertensive rats. J. Cardiovasc. Pharm. 46:842-848.

Jung, O., R.P. Brandes, I. Kim, F. Schweda, R. Schmidt, B.D. Hammock, R. Busse and I. Fleming. 2005. Soluble epoxide hydrolase is a main effector of angiotensin II-induced hypertension. Hypertension. 45:759-765.

Fang, X., N.L. Weintraub, R.B. McCaw, S. Hu, S.D. Harmon, J.B. Rice, B.D. Hammock and A.A. Spector. 2004. Effect of soluble epoxide hydrolase inhibition on epoxyeicosatrienoic acid metabolism in human blood vessels. Am. J. Physiol.-Heart C. 287:H2412-H2420.

In addition to the listed publications, our founder Bruce D. Hammock, Ph.D. has been pioneering the field of s-EH inhibitor research for over 20 years. A compilation of his publications related to this topic can be found here.